Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26123684 | 0.84 | SYK (0.36) | SYKP2RX7 | |
| SCHEMBL30555483 | 0.84 | SYK (0.36) | SYKP2RX7 | |
| SCHEMBL26122222 | 0.78 | SYK (0.34) | SYKP2RX7 | |
| SCHEMBL30555527 | 0.78 | SYK (0.34) | SYKP2RX7 | |
| SCHEMBL22357741 | 0.69 | MPO (0.36) | SYKBRD4 | |
| SCHEMBL30555465 | 0.68 | P2RX7 (0.34) | NTRK1P2RX7 | |
| SCHEMBL26122403 | 0.68 | P2RX7 (0.34) | NTRK1P2RX7 | |
| SCHEMBL30555486 | 0.66 | AXL (0.33) | — | |
| SCHEMBL30555493 | 0.66 | KDM4C (0.37) | NTRK1BRD4 | |
| SCHEMBL23248559 | 0.66 | AXL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021075476-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 | 2021-04-22 | — | — | WO | disclosed |