Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730909 | 0.88 | ALDH1A1 (0.45) | PARP1ALDH1A1KDM4EKMT2APKM | |
| SCHEMBL30159476 | 0.87 | MAP2K4 (0.54) | MAP2K4PARP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL2671519 | 0.87 | MAP2K4 (0.54) | MAP2K4PARP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL23248584 | 0.79 | ALDH1A1 (0.43) | MAP2K4PARP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL14737303 | 0.78 | MAPT (0.50) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL31173872 | 0.78 | MAPT (0.50) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL30159599 | 0.76 | KDM4E (0.50) | MAP2K4PARP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL2569247 | 0.76 | KDM4E (0.50) | MAP2K4PARP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL23559707 | 0.73 | ADORA2A (0.47) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL732566 | 0.73 | IMPDH2 (0.54) | ALDH1A1KDM4EKMT2AHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021075476-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 | 2021-04-22 | — | — | WO | disclosed |