Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | SCN4A | P35499 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.51 |
| ▸ | HEXA | P06865 | 1/20 | 0.49 |
| ▸ | HEXB | P07686 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615269 | 0.83 | SCN9A (0.71) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL16024366 | 0.79 | CYP2D6 (0.45) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL3559632 | 0.78 | CSNK1A1 (0.56) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL743366 | 0.78 | CSNK1A1 (0.56) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL10811842 | 0.78 | SCN9A (0.75) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL975830 | 0.78 | CSNK1A1 (0.72) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL977030 | 0.78 | CSNK1A1 (0.56) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL7542561 | 0.77 | ADORA2A (0.55) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL26645797 | 0.77 | NPC1 (0.48) | ADORA2AHEXAHEXBDHFRDPP4 | |
| SCHEMBL978392 | 0.76 | CYP2D6 (0.58) | CSNK1A1CLK4CYP2D6MAOAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617228-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2017-04-11 | — | — | US | disclosed |
| US-9617228-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160194294-A1 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS | NEKTAR THERAPEUTICS | 2016-07-07 | — | — | US | disclosed |
| US-20160194294-A1 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS | NEKTAR THERAPEUTICS | 2016-07-07 | — | — | US | disclosed |
| US-9266845-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2016-02-23 | — | — | US | disclosed |
| US-9266845-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2016-02-23 | — | — | US | disclosed |
| US-20150065706-A1 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS | NEKTAR THERAPEUTICS | 2015-03-05 | — | — | US | disclosed |
| US-20150065706-A1 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS | NEKTAR THERAPEUTICS | 2015-03-05 | — | — | US | disclosed |
| US-8895553-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895553-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2014-11-25 | — | — | US | disclosed |
| US-8772479-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772479-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772479-B2 | Oligomer-containing substituted aromatic triazine compounds | NEKTAR THERAPEUTICS (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120122871-A1 | Oligomer-Containing Substituted Aromatic Triazine Compounds | NEKTAR THERAPEUTICS (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120122871-A1 | Oligomer-Containing Substituted Aromatic Triazine Compounds | NEKTAR THERAPEUTICS (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120122871-A1 | Oligomer-Containing Substituted Aromatic Triazine Compounds | NEKTAR THERAPEUTICS (US) | 2012-05-17 | — | — | US | disclosed |
| WO-2011095625-A1 | 1,2,4-TRIAZINE-4-AMINE DERIVATIVES | HEPTARES THERAPEUTICS LIMITED (GB) | 2011-08-11 | — | — | WO | disclosed |
| US-4602017-A | Substituted aromatic compounds | SMITHKLINE BEECHAM CORPORATION(A PENNSYLVANIA CORPORATION) | 1986-07-22 | — | — | US | disclosed |
| US-4486354-A | ANTICONVULSANTS | BURROUGH WELLCOME CO. | 1984-12-04 | — | — | US | disclosed |
| EP-0021121-A1 | 1,2,4-Triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122871-A1 | Oligomer-Containing Substituted Aromatic Triazine Compounds | NOD2, HTT, CUL5 | CSNK1A1 4757/4885CLK4 3702/4885CYP2D6 1003/4885 |
| US-20160194294-A1 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS | NOD2, HTT, IPO5 | CSNK1A1 4516/4885CLK4 4221/4885CYP2D6 1051/4885 |
| US-20150065706-A1 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS | NOD2, HTT, IPO5 | CSNK1A1 4516/4885CLK4 4221/4885CYP2D6 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.