Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 10/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 10/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 10/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 9/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 8/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 8/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 8/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258879 | 1.00 | KCNH2 (0.40) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL19662088 | 0.81 | KCNH2 (0.50) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL6866533 | 0.80 | ESR2 (0.45) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL23258881 | 0.79 | HDAC4 (0.44) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL14966664 | 0.74 | PRKAG1 (0.47) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL18394292 | 0.72 | KMT2A (0.54) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL23250727 | 0.72 | HDAC8 (0.55) | HDAC4HDAC2HDAC8TYR | |
| SCHEMBL21471493 | 0.72 | HDAC8 (0.59) | HDAC4HDAC2HDAC8TYRHSP90AA1 | |
| SCHEMBL9772734 | 0.72 | KCNH2 (0.44) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL8266760 | 0.72 | KCNH2 (0.44) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |