SCHEMBL2325159

SCHEMBL2325159

CN1c2ccccc2N(C)c2c1c1ccccc1c1ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.41
GPR3 P46089 1/20 0.40
TTR P02766 1/20 0.37
CES1 P23141 1/20 0.37
BRPF1 P55201 1/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
ADRA2C P18825 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
CCKBR P32239 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
GABRB2 P47870 1/20 0.34
ACHE P22303 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13296005 0.84 ALDH1A1 (0.38) MAOATTRCES1KDM4EMAPT
SCHEMBL12793362 0.78 KDM4E (0.40) KDM4EMAPTALDH1A1GAAHPGD
SCHEMBL482716 0.76 MAOA (0.60) MAOAGPR3TTRCES1BRPF1
SCHEMBL13636983 0.76
SCHEMBL4571020 0.76 MAOA (0.60) MAOAGPR3TTRCES1BRPF1
SCHEMBL29390564 0.76 MAOA (0.60) MAOAGPR3TTRCES1BRPF1
SCHEMBL12776316 0.75 MAPKAPK2 (0.43) MAOAKDM4EMEN1KMT2AADRA2C
SCHEMBL12793283 0.75 TTR (0.40) GPR3TTRCES1KDM4EMAPT
SCHEMBL12793388 0.74 MEN1 (0.40) KDM4EMAPTMEN1MAPK1KMT2A
SCHEMBL12793434 0.74 MAOA (0.57) MAOAMAPTMEN1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
EP-2109898-B1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2011-08-17 EP disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
EP-2109898-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME EASTMAN KODAK COMPANY (US) 2009-10-21 EP disclosed
US-7504163-B2 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY (US) 2009-03-17 US disclosed
WO-2008094399-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME EASTMAN KODAK COMPANY (US) 2008-08-07 WO disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed
US-20070126347-A1 OLEDS with improved efficiency EASTMAN KODAK COMPANY 2007-06-07 US disclosed
US-20060008672-A1 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY 2006-01-12 US disclosed