Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5630969 | 0.84 | CSNK2A2 (0.51) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL10343608 | 0.81 | HTT (0.63) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL19523758 | 0.81 | HTT (0.63) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL16384794 | 0.80 | LIMK1 (0.59) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL16741476 | 0.80 | LIMK1 (0.59) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL16371779 | 0.80 | LIMK1 (0.59) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL18863898 | 0.79 | HTT (0.43) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL14459798 | 0.78 | LIMK1 (0.54) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL16741326 | 0.77 | LIMK1 (0.59) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL16370982 | 0.77 | LIMK1 (0.59) | ALDH1A1CSNK2A2CSNK2BCSNK2A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233866-B1 | PYRAZOLOPYRIDINAMINES AS MKNK1 AND MKNK2 INHIBITORS | Bayer Pharma AG (DE) | 2021-04-21 | — | — | EP | disclosed |