Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14459798 | 0.85 | LIMK1 (0.54) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL23254239 | 0.84 | ALDH1A1 (0.47) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL10343608 | 0.83 | HTT (0.63) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL19523758 | 0.83 | HTT (0.63) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL16370982 | 0.81 | LIMK1 (0.59) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL16741326 | 0.81 | LIMK1 (0.59) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL15534269 | 0.81 | LIMK1 (0.59) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL16385041 | 0.81 | LIMK1 (0.59) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL23254259 | 0.81 | CSNK2A2 (0.50) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 | |
| SCHEMBL15236713 | 0.80 | ALDH1A1 (0.45) | CSNK2A2CSNK2BCSNK2A1LIMK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238701-B2 | Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-20060293322-A1 | Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-12-28 | — | — | US | disclosed |
| EP-1651652-B1 | SUBSTITUTED TETRAHYDROBENZOTHIENOPYRIMIDINAMINE COMPOUNDS USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORP (US) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293322-A1 | Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders | MKI67, PCNA, MYC | CSNK2A2 1481/4885CSNK2B 1875/4885CSNK2A1 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.