Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255103 | 0.97 | HTT (0.42) | HTTSMN1; SMN2CNR2HSD11B1RAB9A | |
| SCHEMBL19382936 | 0.87 | MMP14 (0.48) | HTTSMN1; SMN2HSD11B1RAB9AMEN1 | |
| SCHEMBL10066694 | 0.87 | MMP14 (0.48) | HTTSMN1; SMN2HSD11B1RAB9AMEN1 | |
| SCHEMBL19383057 | 0.83 | MMP14 (0.45) | HTTSMN1; SMN2HSD11B1RAB9AMEN1 | |
| SCHEMBL24795065 | 0.83 | MMP14 (0.45) | HTTSMN1; SMN2HSD11B1RAB9AMEN1 | |
| SCHEMBL20007864 | 0.83 | PTPN5 (0.46) | HTTSMN1; SMN2HSD11B1RAB9AMMP2 | |
| SCHEMBL18407080 | 0.83 | PTPN5 (0.46) | HTTSMN1; SMN2HSD11B1RAB9AMMP2 | |
| SCHEMBL17146887 | 0.83 | NR1H4 (0.50) | HSD11B1MEN1KMT2AMMP2MMP3 | |
| SCHEMBL23255237 | 0.82 | CNR2 (0.33) | HTTSMN1; SMN2CNR2RAB9AMEN1 | |
| SCHEMBL24513216 | 0.82 | HTT (0.51) | HTTSMN1; SMN2CNR2HSD11B1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850368-B2 | FILM FORMING COMPOSITION AND ORGANIC ELECTROLUMINESCENT DEVICE | PIONEER CORP (JP) | 2021-04-21 | — | — | EP | disclosed |