Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18407080 | 1.00 | PTPN5 (0.46) | PTPN5MMP14MMP2MMP3MMP9 | |
| SCHEMBL10066694 | 0.96 | MMP14 (0.48) | PTPN5MMP14MMP2MMP3MMP9 | |
| SCHEMBL19382936 | 0.96 | MMP14 (0.48) | PTPN5MMP14MMP2MMP3MMP9 | |
| SCHEMBL19383057 | 0.91 | MMP14 (0.45) | PTPN5MMP14MMP2MMP3MMP9 | |
| SCHEMBL24795065 | 0.91 | MMP14 (0.45) | PTPN5MMP14MMP2MMP3MMP9 | |
| SCHEMBL17146887 | 0.91 | NR1H4 (0.50) | PTPN5MMP14MMP2MMP3MMP9 | |
| SCHEMBL26212824 | 0.89 | ALDH1A1 (0.52) | ALDH1A1NPC1MAPTHPGDMAPK1 | |
| SCHEMBL21891939 | 0.89 | PTPN5 (0.44) | PTPN5MMP14MMP2MMP3MMP9 | |
| SCHEMBL23255103 | 0.88 | HTT (0.42) | PTPN5MMP14MMP2MMP3MMP9 | |
| SCHEMBL20837008 | 0.88 | RAB9A (0.53) | PTPN5NR1H4PTGESACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2843743-B1 | Membrane electrode units for high temperature fuel cells with improved stability | BASF SE (DE) | 2018-03-28 | — | — | EP | disclosed |