Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.48 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835360 | 0.86 | TSHR (0.52) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL837428 | 0.83 | MEN1 (0.55) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL3121131 | 0.82 | MEN1 (0.54) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL837415 | 0.79 | TSHR (0.49) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL3223903 | 0.78 | PDE4A (0.55) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL8668035 | 0.78 | PNP (0.53) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL19066322 | 0.76 | RXFP1 (0.59) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL19066314 | 0.76 | MEN1 (0.65) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL836619 | 0.76 | MEN1 (0.77) | MEN1KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL9853392 | 0.75 | MEN1 (0.53) | TSHRMEN1KMT2AHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251675-B1 | PREVENTION OR TREATMENT OF URIC ACID OR GOUT DISEASE | SHANTON PHARMA PTE LTD (SG) | 2021-04-21 | — | — | EP | disclosed |