Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | BRD2 | P25440 | 2/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.49 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320101 | 0.93 | MEN1 (0.52) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL8914154 | 0.89 | MEN1 (0.57) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL9853394 | 0.81 | ADORA2B (0.45) | MEN1KMT2AALDH1A1NPC1POLB | |
| SCHEMBL19066314 | 0.80 | MEN1 (0.65) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL9298051 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL19066322 | 0.78 | RXFP1 (0.59) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL19090458 | 0.76 | ALDH1A1 (0.55) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL23255226 | 0.75 | TSHR (0.56) | MEN1KMT2ANPSR1ALDH1A1BRD4 | |
| SCHEMBL7326739 | 0.75 | MEN1 (0.77) | MEN1KMT2AALDH1A1BRD4BRD2 | |
| SCHEMBL3223903 | 0.74 | PDE4A (0.55) | MEN1KMT2ANPSR1ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965271-A | Method of inhibiting the activity of leukocyte derived cytokines | HOECHST ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-10-23 | — | — | US | claimed |
| EP-0421587-A2 | Xanthine derivatives used in asthma | Beecham Group p.l.c. (GB) | 1991-04-10 | — | — | EP | disclosed |