Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255294 | 0.94 | PDE10A (0.39) | KIF11PDE10APDE2APDE7APTGDR2 | |
| SCHEMBL23255677 | 0.94 | KIF11 (0.40) | KIF11PDE10APDE2APDE7APTGDR2 | |
| SCHEMBL23255319 | 0.93 | KIF11 (0.40) | KIF11PDE10APDE2APDE7APTGDR2 | |
| SCHEMBL23255426 | 0.92 | KIF11 (0.40) | KIF11PDE10APDE2APDE7AHSP90AA1 | |
| SCHEMBL23255416 | 0.92 | PDE10A (0.36) | KIF11PDE10APDE2APDE7APIK3CA | |
| SCHEMBL23255415 | 0.90 | ICMT (0.36) | KIF11PDE10AGRIN1HTR6CYP17A1 | |
| SCHEMBL23255425 | 0.88 | KIF11 (0.37) | KIF11PDE10APDE2APDE7AHSP90AA1 | |
| SCHEMBL23255428 | 0.88 | KIF11 (0.37) | KIF11PDE10APDE2APDE7AHSP90AA1 | |
| SCHEMBL23255277 | 0.88 | KIF11 (0.40) | KIF11PDE10APDE2APDE7APTGDR2 | |
| SCHEMBL23255676 | 0.88 | PDE10A (0.41) | KIF11PDE10APDE2APDE7APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |