Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255689 | 0.94 | PDE10A (0.37) | PDE10AKIF11PDE2APDE7ACYP1A2 | |
| SCHEMBL23255416 | 0.93 | PDE10A (0.36) | PDE10AKIF11PDE2APDE7ACYP1A2 | |
| SCHEMBL23255436 | 0.92 | ICMT (0.36) | PDE10AKIF11PDE2APDE7AICMT | |
| SCHEMBL23255319 | 0.92 | KIF11 (0.40) | PDE10AKIF11PDE2APDE7ACYP1A2 | |
| SCHEMBL23255267 | 0.90 | CYP11B1 (0.38) | PDE10AKIF11PDE2APDE7AS1PR1 | |
| SCHEMBL23255435 | 0.89 | GPBAR1 (0.39) | PDE10AKIF11PDE2APDE7ACYP1A2 | |
| SCHEMBL23255272 | 0.88 | KIF11 (0.41) | PDE10AKIF11PDE2APDE7ACYP1A2 | |
| SCHEMBL23255600 | 0.87 | KIF11 (0.39) | KIF11CYP3A4NPY5RGPBAR1 | |
| SCHEMBL23255590 | 0.87 | KIF11 (0.43) | PDE10AKIF11PDE2APDE7ACYP1A2 | |
| SCHEMBL23255317 | 0.86 | PDE10A (0.40) | PDE10AKIF11PDE2APDE7ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |