Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325146 | 0.82 | WDR5 (0.41) | WDR5KDM4EPOLBSMN1; SMN2NCEH1 | |
| SCHEMBL6748668 | 0.82 | WDR5 (0.68) | WDR5LDHAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL27927917 | 0.79 | WDR5 (0.59) | WDR5LDHAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL3196806 | 0.77 | WDR5 (0.58) | WDR5LDHAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL2328644 | 0.77 | SLC22A12 (0.46) | WDR5KDM4EPOLBSIGMAR1KMT2A | |
| SCHEMBL28474429 | 0.75 | WDR5 (0.44) | WDR5KDM4ESMN1; SMN2NCEH1SIGMAR1 | |
| SCHEMBL2329249 | 0.73 | WDR5 (0.56) | WDR5LDHAKDM4ENCEH1KMT2A | |
| SCHEMBL12441442 | 0.72 | WDR5 (0.51) | WDR5LDHAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL29876488 | 0.72 | WDR5 (0.55) | WDR5LDHAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL1614544 | 0.72 | SIGMAR1 (0.67) | SIGMAR1GAATDP1NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2357177-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | Kyoto University (JP) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010047318-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | 国立大学法人京都大学 (JP) | 2010-04-29 | — | — | WO | disclosed |