Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438479 | 1.00 | HRH3 (1.00) | HRH3 | |
| SCHEMBL449365 | 1.00 | HRH3 (1.00) | HRH3 | |
| SCHEMBL12128213 | 1.00 | HRH3 (1.00) | HRH3 | |
| SCHEMBL12128226 | 1.00 | HRH3 (1.00) | HRH3 | |
| SCHEMBL12130263 | 0.87 | HRH3 (0.77) | HRH3 | |
| SCHEMBL15314516 | 0.86 | HRH3 (1.00) | HRH3 | |
| SCHEMBL438593 | 0.86 | HRH3 (1.00) | HRH3 | |
| SCHEMBL437389 | 0.86 | HRH3 (1.00) | HRH3 | |
| SCHEMBL449397 | 0.86 | HRH3 (1.00) | HRH3 | |
| SCHEMBL437374 | 0.85 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673146-A2 | METHODS FOR TREATING OBSESSIVE COMPULSIVE RELATED DISORDERS, TIC DISORDERS AND GLUTAMATE EXCITOTOXICITY RELATED DISORDERS | Biohaven Therapeutics Ltd. (VG) | 2026-01-07 | — | — | EP | claimed |
| WO-2024182465-A2 | METHODS FOR TREATING OBSESSIVE COMPULSIVE RELATED DISORDERS, TIC DISORDERS AND GLUTAMATE EXCITOTOXICITY RELATED DISORDERS | ALCO THERAPEUTICS, LLC (US) | 2024-09-06 | — | — | WO | claimed |
| EP-4251148-A1 | HISTAMINE H3 RECEPTOR ANTAGONISTS/INVERSE AGONISTS FOR THE TREATMENT OF AUTISM SPECTRUM DISORDER | Richter Gedeon Nyrt. (HU) | 2023-10-04 | — | — | EP | claimed |
| WO-2022113008-A1 | HISTAMINE H3 RECEPTOR ANTAGONISTS/INVERSE AGONISTS FOR THE TREATMENT OF AUTISM SPECTRUM DISORDER | RICHTER GEDEON NYRT. (HU) | 2022-06-02 | — | — | WO | claimed |
| US-20110201623-A1 | Crystalline Form Of A Cyclopropyl Benzamide Derivative | ASTRAZENECA PHARMACEUTICALS LP | 2011-08-18 | — | — | US | claimed |
| EP-4673146-A2 | METHODS FOR TREATING OBSESSIVE COMPULSIVE RELATED DISORDERS, TIC DISORDERS AND GLUTAMATE EXCITOTOXICITY RELATED DISORDERS | Biohaven Therapeutics Ltd. (VG) | 2026-01-07 | — | — | EP | disclosed |
| US-20250344963-A1 | METHODS FOR ACQUIRING AND ANALYZING NEUROMELANIN-SENSITIVE MRI | UNIV OF OTTAWA INSTITUTE OF MENTAL HEALTH RESEARCH (CA) | 2025-11-13 | — | — | US | disclosed |
| US-20250195477-A1 | DEUTERATED IDAZOXAN AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC. | 2025-06-19 | — | — | US | disclosed |
| EP-4479365-A1 | DEUTERATED IDAZOXAN AND METHODS OF USE THEREOF | Terran Biosciences Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| CN-119053573-A | Deuterated imidazole kesheng and methods of use thereof | 人类生物科学股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| WO-2024182465-A2 | METHODS FOR TREATING OBSESSIVE COMPULSIVE RELATED DISORDERS, TIC DISORDERS AND GLUTAMATE EXCITOTOXICITY RELATED DISORDERS | ALCO THERAPEUTICS, LLC (US) | 2024-09-06 | — | — | WO | disclosed |
| WO-2023235766-A2 | METHODS FOR ACQUIRING AND ANALYZING NEUROMELANIN-SENSITIVE MRI | UNIVERSITY OF OTTAWA INSTITUTE OF MENTAL HEALTH RESEARCH (CA) | 2023-12-07 | — | — | WO | disclosed |
| US-20130172560-A1 | PROCESSES FOR MAKING CYCLOPROPYL AMIDE DERIVATIVES AND INTERMEDIATES ASSOCIATED THEREWITH | ASTRAZENECA AB (SE) | 2013-07-04 | — | — | US | disclosed |
| EP-2536702-A1 | NEW CRYSTALLINE FORM OF A CYCLOPROPYL BENZAMIDE DERIVATIVE | AstraZeneca AB (SE) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011102795-A1 | NEW CRYSTALLINE FORM OF A CYCLOPROPYL BENZAMIDE DERIVATIVE | ASTRAZENECA AB (SE) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011102795-A1 | NEW CRYSTALLINE FORM OF A CYCLOPROPYL BENZAMIDE DERIVATIVE | ASTRAZENECA AB (SE) | 2011-08-25 | — | — | WO | disclosed |
| US-20110201623-A1 | Crystalline Form Of A Cyclopropyl Benzamide Derivative | ASTRAZENECA PHARMACEUTICALS LP | 2011-08-18 | — | — | US | disclosed |
| US-20110201623-A1 | Crystalline Form Of A Cyclopropyl Benzamide Derivative | ASTRAZENECA PHARMACEUTICALS LP | 2011-08-18 | — | — | US | disclosed |
| US-20110201623-A1 | Crystalline Form Of A Cyclopropyl Benzamide Derivative | ASTRAZENECA PHARMACEUTICALS LP | 2011-08-18 | — | — | US | disclosed |
| US-20110201623-A1 | Crystalline Form Of A Cyclopropyl Benzamide Derivative | ASTRAZENECA PHARMACEUTICALS LP | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172560-A1 | PROCESSES FOR MAKING CYCLOPROPYL AMIDE DERIVATIVES AND INTERMEDIATES ASSOCIATED THEREWITH | HRH4, HRH2, HRH3 | HRH3 3/4885 |
| US-20250195477-A1 | DEUTERATED IDAZOXAN AND METHODS OF USE THEREOF | XDH, INA, SLC6A3 | HRH3 488/4885 |
| US-20110201623-A1 | Crystalline Form Of A Cyclopropyl Benzamide Derivative | GBA1, BAK1, BBC3 | HRH3 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.