SCHEMBL23258183

SCHEMBL23258183

c1cc(-c2ccc(N(c3ccc(-c4ccc5ccccc5c4)cc3)c3cccc4c3sc3ccccc34)cc2)cc(-c2cc3ccccc3c3ccccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
S1PR5 Q9H228 8/20 0.34
S1PR4 O95977 6/20 0.34
GPR84 Q9NQS5 1/20 0.32
CYP11B1 P15538 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
GSTP1 P09211 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24839180 0.96 ALOX5 (0.37) ALOX5S1PR5S1PR4GPR84CYP11B1
SCHEMBL23258162 0.96 ALOX5 (0.38) ALOX5S1PR5S1PR4GPR84CYP11B1
SCHEMBL23225052 0.93 ALOX5 (0.36) ALOX5S1PR5S1PR4CYP11B1HSD17B1
SCHEMBL24839091 0.93 ALOX5 (0.39) ALOX5S1PR5S1PR4GPR84CYP11B1
SCHEMBL23258159 0.92 ALOX5 (0.38) ALOX5GPR84CYP11B1HSD17B1HSD17B2
SCHEMBL23179197 0.91 ALOX5 (0.38) ALOX5S1PR5S1PR4HSD17B1HSD17B2
SCHEMBL24842206 0.91 ALOX5 (0.38) ALOX5S1PR5S1PR4HSD17B1HSD17B2
SCHEMBL23179191 0.91 ALOX5 (0.38) ALOX5S1PR5S1PR4HSD17B1HSD17B2
SCHEMBL24841830 0.91 ALOX5 (0.38) ALOX5S1PR5S1PR4HSD17B1HSD17B2
SCHEMBL23180165 0.91 ALOX5 (0.38) ALOX5S1PR5S1PR4HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210119135-A1 LUMINESCENCE DEVICE AND AMINE COMPOUND FOR LUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210119135-A1 LUMINESCENCE DEVICE AND AMINE COMPOUND FOR LUMINESCENCE DEVICE SLC18A1, SLC29A1, SAT1 ALOX5 1578/4885S1PR5 4122/4885S1PR4 3996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.