Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 4/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258511 | 0.79 | ELANE (0.50) | ELANEPARP10KDM1AALDH1A1LMNA | |
| SCHEMBL23258832 | 0.75 | PDE4B (0.40) | ELANEPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL23258874 | 0.75 | ELANE (0.45) | ELANEKDM1AALDH1A1GPR119LMNA | |
| SCHEMBL23258827 | 0.75 | ELANE (0.45) | ELANEKDM1AALDH1A1LMNAMAPT | |
| SCHEMBL23258611 | 0.75 | ELANE (0.46) | ELANEACACBPARP10KDM1AALDH1A1 | |
| SCHEMBL23258808 | 0.75 | ELANE (0.46) | ELANEPARP10ALDH1A1LMNAMAPT | |
| SCHEMBL23258525 | 0.74 | KDM1A (0.42) | ELANEKDM1APDE4BPDE4APDE4C | |
| SCHEMBL23258561 | 0.74 | ELANE (0.44) | ELANEKDM1AMAPT | |
| SCHEMBL23249891 | 0.74 | ELANE (0.44) | ELANEKDM1ALMNAMAPT | |
| SCHEMBL27018128 | 0.74 | ELANE (0.44) | ELANEKDM1AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |