Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 3/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259175 | 0.75 | KDM1A (0.41) | KDM1AELANEPDE4BPDE4APDE4C | |
| SCHEMBL23258463 | 0.74 | ELANE (0.42) | KDM1AELANEPDE4BPDE4APDE4C | |
| SCHEMBL23259163 | 0.74 | KDM1A (0.39) | KDM1AELANEPDE4BPDE4APDE4C | |
| SCHEMBL23258827 | 0.73 | ELANE (0.45) | KDM1AELANESLC6A2AR | |
| SCHEMBL23258874 | 0.73 | ELANE (0.45) | KDM1AELANE | |
| SCHEMBL23258889 | 0.73 | KDM1A (0.36) | KDM1AELANEPDE4BPDE4APDE4C | |
| SCHEMBL23259206 | 0.73 | QDPR (0.47) | KDM1APDE4B | |
| SCHEMBL23249891 | 0.72 | ELANE (0.44) | KDM1AELANE | |
| SCHEMBL23258561 | 0.72 | ELANE (0.44) | KDM1AELANE | |
| SCHEMBL27018128 | 0.72 | ELANE (0.44) | KDM1AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |