Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258869 | 0.78 | ELANE (0.42) | ELANEMTNR1AMTNR1BHSD17B10RIPK1 | |
| SCHEMBL18263215 | 0.74 | ELANE (0.47) | ELANEMTNR1AMTNR1BHSD17B10RIPK1 | |
| SCHEMBL23249868 | 0.70 | ELANE (0.41) | ELANEMTNR1AMTNR1BRIPK1CTSS | |
| SCHEMBL23057965 | 0.70 | BRD4 (0.41) | GABRA1GABRB2ELANEHSD17B10BRD4 | |
| SCHEMBL29575324 | 0.69 | ELANE (0.38) | ELANEBRD4 | |
| SCHEMBL15867197 | 0.69 | ELANE (0.38) | ELANEBRD4 | |
| SCHEMBL23628554 | 0.69 | KDM4E (0.40) | ELANEHSD17B10 | |
| SCHEMBL2221010 | 0.69 | ELANE (0.49) | ELANEHSD17B10BRD4 | |
| SCHEMBL2761277 | 0.69 | ELANE (0.49) | ELANEHSD17B10L3MBTL1 | |
| SCHEMBL12948194 | 0.69 | PPARA (0.49) | GABRA1GABRB2ELANEHSD17B10BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |