Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258869 | 0.86 | ELANE (0.42) | ELANENPC1RAB9AMEN1HTT | |
| SCHEMBL23258470 | 0.85 | ELANE (0.39) | ELANENPC1RAB9AMEN1HTT | |
| SCHEMBL23259156 | 0.82 | ELANE (0.40) | ELANENPC1RAB9AMEN1HTT | |
| SCHEMBL28337676 | 0.82 | HSD17B10 (0.35) | MEN1KMT2ACA2HSD17B10CA1 | |
| SCHEMBL21503790 | 0.80 | ELANE (0.46) | ELANENPC1RAB9AMEN1HTT | |
| SCHEMBL2761277 | 0.79 | ELANE (0.49) | ELANEMEN1KMT2AKDM1ASMN1; SMN2 | |
| SCHEMBL2221010 | 0.79 | ELANE (0.49) | ELANEKMT2AKDM1ACA2HSD17B10 | |
| SCHEMBL23258801 | 0.79 | SCN5A (0.40) | ELANECA2CA1 | |
| SCHEMBL13244538 | 0.78 | ELANE (0.47) | ELANEKDM1ACA2 | |
| SCHEMBL27259478 | 0.78 | ELANE (0.47) | ELANENPC1RAB9AKDM1ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108416-B | Preparation method of 1, 2-dicyclopropylethylphenol and optical isomer thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-107108416-A | A kind of preparation method of 1,2 Bicyclopropyl ethyl -phenol and its optical isomer | 四川海思科制药有限公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2016188490-A1 | METHOD FOR PREPARING 1,2-DICYCLOPROPYLETHYLPHENOL AND OPTICAL ISOMER THEREOF | 四川海思科制药有限公司 | 2016-12-01 | — | — | WO | disclosed |
| WO-2016188490-A1 | METHOD FOR PREPARING 1,2-DICYCLOPROPYLETHYLPHENOL AND OPTICAL ISOMER THEREOF | 四川海思科制药有限公司 | 2016-12-01 | — | — | WO | disclosed |