Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258503 | 0.86 | KDM1A (0.37) | KDM1AMAOBELANEOPRM1OPRD1 | |
| SCHEMBL23259163 | 0.85 | KDM1A (0.39) | SLC6A4SLC6A3KDM1AELANEPDE4B | |
| SCHEMBL23258884 | 0.81 | HDAC4 (0.35) | KDM1AMAOBELANEPDE4BHDAC4 | |
| SCHEMBL23258720 | 0.79 | MGLL (0.33) | KDM1AMAOBELANEPDE4BHDAC4 | |
| SCHEMBL23258495 | 0.74 | SLC6A3 (0.45) | SLC6A4SLC6A3 | |
| SCHEMBL23259212 | 0.72 | CYP3A4 (0.44) | ELANEHDAC4HDAC2HDAC8 | |
| SCHEMBL23250778 | 0.72 | HDAC4 (0.47) | SLC6A4SLC6A3OPRM1OPRD1HDAC4 | |
| SCHEMBL23249868 | 0.71 | ELANE (0.41) | ELANE | |
| SCHEMBL23258871 | 0.71 | ELANE (0.41) | ELANE | |
| SCHEMBL23259167 | 0.70 | PARP1 (0.44) | ELANEHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |