Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259223 | 0.85 | AAK1 (0.40) | ELANEPTGDR2MTNR1AMTNR1BAAK1 | |
| SCHEMBL23258477 | 0.83 | PKM (0.40) | ELANEMTNR1AMTNR1BRAB9ASMN1; SMN2 | |
| SCHEMBL23259153 | 0.81 | ELANE (0.42) | ELANEMTNR1AMTNR1BAAK1NPC1 | |
| SCHEMBL18089691 | 0.81 | ELANE (0.42) | ELANEPTGDR2AAK1NPC1RAB9A | |
| SCHEMBL23258507 | 0.79 | AAK1 (0.46) | ELANEPTGDR2MTNR1AMTNR1BAAK1 | |
| SCHEMBL23249868 | 0.79 | ELANE (0.41) | ELANEMTNR1AMTNR1BAAK1NPC1 | |
| SCHEMBL23258536 | 0.78 | PKM (0.43) | ELANEMTNR1AMTNR1BAAK1NPC1 | |
| SCHEMBL23259165 | 0.78 | ELANE (0.40) | HSP90AA1ELANEMTNR1AMTNR1BAAK1 | |
| SCHEMBL29233767 | 0.78 | PTGDR2 (0.40) | ELANEPTGDR2MTNR1AMTNR1BAAK1 | |
| SCHEMBL18857940 | 0.77 | ELANE (0.41) | ELANEMTNR1AMTNR1BNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |