Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259223 | 0.89 | AAK1 (0.40) | AAK1USP30ELANEDGAT1PTGDR2 | |
| SCHEMBL23258883 | 0.84 | ELANE (0.40) | AAK1ELANEALDH1A1RAB9AMTNR1A | |
| SCHEMBL23258536 | 0.81 | PKM (0.43) | AAK1ELANESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23258501 | 0.79 | HSP90AA1 (0.42) | AAK1ELANEPTGDR2SMN1; SMN2NPC1 | |
| SCHEMBL23258509 | 0.79 | HRH3 (0.41) | ELANE | |
| SCHEMBL23258554 | 0.78 | ELANE (0.35) | ELANEMTNR1AMTNR1B | |
| SCHEMBL14839466 | 0.77 | ELANE (0.44) | ELANEMAPK1RAB9AHTTMTNR1A | |
| SCHEMBL23249891 | 0.77 | ELANE (0.44) | AAK1ELANEPTGDR2SMN1; SMN2NPC1 | |
| SCHEMBL23258826 | 0.77 | ELANE (0.41) | ELANEMAPT | |
| SCHEMBL18089691 | 0.76 | ELANE (0.42) | AAK1USP30ELANEPTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |