Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30465990 | 0.87 | ACHE (0.43) | CTNNB1WNT3AACHELMNAMAPT | |
| SCHEMBL7516624 | 0.87 | ACHE (0.43) | CTNNB1WNT3AACHELMNAMAPT | |
| Bicarbonate SCHEMBL9415505 | 0.83 | CTNNB1 (0.44) | CTNNB1WNT3AACHELMNAMAPT | |
| SCHEMBL16361854 | 0.77 | CTNNB1 (0.37) | CTNNB1WNT3AACHEMAPTHPGD | |
| SCHEMBL16323362 | 0.77 | CTNNB1 (0.37) | CTNNB1WNT3AACHEMAPTHPGD | |
| SCHEMBL5785526 | 0.76 | PARP1 (0.47) | CTNNB1WNT3ALMNAMAPTPARP1 | |
| SCHEMBL23258708 | 0.76 | PARP1 (0.40) | CLK1DYRK1ADYRK1BPARP1HTR2A | |
| SCHEMBL1181324 | 0.75 | MAPT (0.46) | CTNNB1WNT3AACHELMNAMAPT | |
| SCHEMBL8255618 | 0.75 | HTR7 (0.46) | ACHE | |
| SCHEMBL8255617 | 0.74 | SCN9A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |