Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.49 |
| ▸ | LPL | P06858 | 7/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985660 | 0.92 | DGAT1 (0.49) | DGAT1LIPGLPLKEAP1NFE2L2 | |
| SCHEMBL17474563 | 0.83 | DGAT1 (0.54) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL3761944 | 0.82 | DGAT1 (0.50) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL298401 | 0.81 | DGAT1 (0.72) | DGAT1LIPGLPLCA9CA1 | |
| SCHEMBL3767677 | 0.81 | DGAT1 (0.52) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL182480 | 0.80 | DGAT1 (0.51) | DGAT1LIPGLPLEGFRMAPK1 | |
| SCHEMBL15884409 | 0.80 | EGFR (0.52) | DGAT1LIPGLPLEGFR | |
| SCHEMBL31750228 | 0.80 | DGAT1 (0.51) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL24058035 | 0.80 | DGAT1 (0.51) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL28738862 | 0.80 | DGAT1 (0.51) | DGAT1LIPGLPLEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |