Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761277 | 0.84 | ELANE (0.49) | ELANEALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL18263215 | 0.82 | ELANE (0.47) | ELANEHSD17B10MEN1KMT2ANPC1 | |
| SCHEMBL23258769 | 0.82 | ELANE (0.40) | ELANEALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23258801 | 0.82 | SCN5A (0.40) | ELANEHPGDTSHRCA2 | |
| SCHEMBL23258470 | 0.78 | ELANE (0.39) | ELANEALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL27281232 | 0.77 | ELANE (0.42) | ELANEALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23258869 | 0.77 | ELANE (0.42) | ELANEALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL23259153 | 0.77 | ELANE (0.42) | ELANEALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23263854 | 0.77 | GAA (0.39) | ELANEALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23628555 | 0.76 | KDM4E (0.64) | ELANEALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |