Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489261 | 0.88 | KDM4E (0.47) | KDM4EHPGDHSD17B10ALDH1A1ELANE | |
| SCHEMBL15867195 | 0.88 | KDM4E (0.47) | KDM4EHPGDHSD17B10ALDH1A1ELANE | |
| SCHEMBL2761277 | 0.87 | ELANE (0.49) | KDM4EHPGDHSD17B10ALDH1A1ELANE | |
| SCHEMBL23628554 | 0.80 | KDM4E (0.40) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL6058719 | 0.79 | KDM4E (0.66) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL27281232 | 0.79 | ELANE (0.42) | KDM4EHPGDHSD17B10ALDH1A1ELANE | |
| SCHEMBL1315833 | 0.78 | KDM4E (1.00) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL29760302 | 0.78 | KDM4E (1.00) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL1606328 | 0.78 | ALDH1A1 (0.58) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL28317244 | 0.76 | ALDH1A1 (0.71) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3978488-A1 | ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Universitetet I Oslo (NO) | 2022-04-06 | — | — | EP | disclosed |
| EP-3497095-B1 | ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | UNIV OSLO (NO) | 2021-07-14 | — | — | EP | disclosed |