Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 3/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259154 | 0.76 | ELANE (0.36) | ELANEKDM1AMEN1KMT2AATM | |
| SCHEMBL23258503 | 0.74 | KDM1A (0.37) | ELANEKDM1AGPR119MAOB | |
| SCHEMBL23258869 | 0.73 | ELANE (0.42) | ELANEKDM1AMEN1KMT2AKDM4E | |
| SCHEMBL23258870 | 0.73 | ELANE (0.33) | ELANEKDM1AGPR119 | |
| SCHEMBL23259175 | 0.72 | KDM1A (0.41) | ELANEKDM1A | |
| SCHEMBL23258832 | 0.70 | PDE4B (0.40) | ELANE | |
| SCHEMBL23250755 | 0.67 | DBH (0.43) | RBP4 | |
| SCHEMBL23263208 | 0.67 | ELANE (0.37) | ELANEMEN1KMT2A | |
| SCHEMBL1790296 | 0.66 | PTGDR2 (0.52) | ELANEMEN1KMT2A | |
| SCHEMBL2223556 | 0.65 | ELANE (0.52) | ELANEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |