Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259163 | 0.85 | KDM1A (0.39) | KDM1AELANEPDE4BPDE4APDE4C | |
| SCHEMBL23258503 | 0.83 | KDM1A (0.37) | KDM1AELANEPDE4BPDE4APDE4C | |
| SCHEMBL23259206 | 0.79 | QDPR (0.47) | KDM1APDE4BNAMPT | |
| SCHEMBL23258889 | 0.79 | KDM1A (0.36) | KDM1AELANEPDE4BPDE4APDE4C | |
| SCHEMBL23258827 | 0.76 | ELANE (0.45) | KDM1AELANEBRD4 | |
| SCHEMBL23258874 | 0.76 | ELANE (0.45) | KDM1AELANEBRD4 | |
| SCHEMBL23258525 | 0.75 | KDM1A (0.42) | KDM1AELANEPDE4BPDE4APDE4C | |
| SCHEMBL23258561 | 0.75 | ELANE (0.44) | KDM1AELANEBRD4 | |
| SCHEMBL23249891 | 0.75 | ELANE (0.44) | KDM1AELANEBRD4 | |
| SCHEMBL27018128 | 0.75 | ELANE (0.44) | KDM1AELANEBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |