SCHEMBL23259754

SCHEMBL23259754

O=C(O)c1cc2c(cc1-c1cc3c4ccccc4n(-c4ccccc4)c3cc1C(=O)O)c1ccccc1n2-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
ATM Q13315 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ALDH1A1 P00352 3/20 0.53
KMT2A Q03164 1/20 0.47
NOTUM Q6P988 2/20 0.44
TSHR P16473 1/20 0.44
FOLH1 Q04609 2/20 0.43
RECQL P46063 1/20 0.43
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
GAA P10253 1/20 0.40
GFER P55789 1/20 0.40
PTPN1 P18031 2/20 0.40
POLB P06746 1/20 0.40
HDAC4 P56524 1/20 0.39
PPARG P37231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23260020 0.94 ALDH1A1 (0.51) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL23259765 0.88 ALDH1A1 (0.51) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL23259755 0.84 NR4A2 (0.53) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL2790066 0.84 KDM4E (0.51) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL17433211 0.81 L3MBTL1 (0.72) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL23260019 0.80 NR4A2 (0.49) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL1638441 0.79 L3MBTL1 (0.82) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL27426967 0.79 L3MBTL1 (0.82) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL23017007 0.78 L3MBTL1 (0.67) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL17431207 0.78 L3MBTL1 (0.67) KDM4EATML3MBTL1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210115059-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS Shanghai Tianma AM-OLED Co., Ltd. (CN) 2021-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115059-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS CNKSR1, C1S, ARRB1 KDM4E 3667/4885ATM 3917/4885L3MBTL1 1337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.