Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22010250 | 0.72 | PDK2 (0.46) | PDK2PDK4HTR5AATMALDH1A1 | |
| SCHEMBL18403613 | 0.68 | PDK2 (0.43) | PDK2PDK4HTR5AATMALDH1A1 | |
| SCHEMBL9791466 | 0.68 | PDK2 (0.43) | PDK2PDK4HTR5AATMALDH1A1 | |
| Iodide SCHEMBL28085903 | 0.67 | PDK2 (0.42) | PDK2PDK4HTR5AATMALDH1A1 | |
| SCHEMBL24390038 | 0.65 | PDK2 (0.60) | PDK2PDK4ATMALDH1A1HSD17B10 | |
| SCHEMBL15468271 | 0.65 | PDK2 (0.41) | PDK2PDK4HTR5AATMALDH1A1 | |
| SCHEMBL24166676 | 0.65 | ATM (0.42) | PDK2PDK4HTR5AATMALDH1A1 | |
| SCHEMBL29371027 | 0.64 | PDK2 (0.67) | PDK2PDK4HTR5ACYP3A4TDP1 | |
| SCHEMBL31911 | 0.64 | PDK2 (0.67) | PDK2PDK4HTR5ACYP3A4TDP1 | |
| SCHEMBL11737130 | 0.64 | PGR (0.51) | PDK2PDK4HTR5AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210113712-A1 | METHODS FOR PREPARING CELL TARGETING CONJUGATES AND CONJUGATES OBTAINABLE BY SAID METHODS | LINXIS B V (NL) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113712-A1 | METHODS FOR PREPARING CELL TARGETING CONJUGATES AND CONJUGATES OBTAINABLE BY SAID METHODS | CD47, EPCAM, CD44 | PDK2 3572/4885PDK4 4277/4885HTR5A 4168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.