Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718388 | 0.72 | — | — | |
| SCHEMBL17008902 | 0.65 | CSNK2A1 (0.42) | ADORA2BALDH1A1MEN1POLBKMT2A | |
| SCHEMBL17020156 | 0.64 | ADORA2B (0.41) | ADORA2BALDH1A1MEN1POLBKMT2A | |
| SCHEMBL23246540 | 0.62 | ADORA2B (0.52) | ADORA2BALDH1A1MEN1POLBKMT2A | |
| SCHEMBL17008879 | 0.62 | LMNA (0.42) | ADORA2BALDH1A1MEN1POLBKMT2A | |
| SCHEMBL10652515 | 0.57 | ADORA2B (1.00) | ADORA2BALDH1A1POLBPDE4AADORA2A | |
| SCHEMBL1956056 | 0.57 | — | — | |
| SCHEMBL6362430 | 0.57 | KDM4E (0.43) | ALDH1A1MEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL20888904 | 0.56 | ADORA2B (0.36) | ADORA2BALDH1A1MEN1POLBKMT2A | |
| SCHEMBL27404798 | 0.54 | ADORA2B (0.34) | ADORA2BPOLBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021074198-A1 | NOVEL TETRAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-04-22 | — | — | WO | disclosed |