SCHEMBL2326314

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2324168	0.85	ALK (0.42)	RET
	SCHEMBL13968476	0.83	CYP3A4 (0.41)	RETCYP3A4CYP3A5GBA1
	SCHEMBL2321632	0.82	MET (0.47)	CYP3A4CYP3A5
	SCHEMBL2324885	0.82	PRKCQ (0.46)	—
	SCHEMBL12440312	0.82	GBA1 (0.45)	RETCYP3A4GBA1WNT3ACKS1B
	Hydrochloric Acid SCHEMBL2327479	0.81	PRKCQ (0.45)	—
	SCHEMBL13834756	0.80	TDO2 (0.45)	RET
	SCHEMBL28462137	0.79	RET (0.54)	RETADKPGK1GBA1WNT3A
	SCHEMBL31071888	0.79	RET (0.54)	RETADKPGK1GBA1WNT3A
	SCHEMBL10153130	0.78	RET (0.50)	RETWNT3ACKS1BSKP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.