Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4121532 | 0.78 | TP53 (0.32) | ALDH1A1 | |
| SCHEMBL2185566 | 0.70 | DGAT1 (0.41) | DGAT1ALDH1A1KCNN4 | |
| SCHEMBL21605368 | 0.70 | PIK3CD (0.35) | KDM4E | |
| SCHEMBL65055 | 0.70 | DGAT1 (0.41) | DGAT1ALDH1A1KCNN4 | |
| SCHEMBL2184251 | 0.70 | DGAT1 (0.41) | DGAT1ALDH1A1KCNN4 | |
| SCHEMBL12563721 | 0.70 | ELANE (0.43) | MAPTDGAT1ALDH1A1PKMKDM4E | |
| SCHEMBL20959675 | 0.69 | DGAT1 (0.39) | DGAT1ALDH1A1KCNN4 | |
| Ammonia Solution, Strong SCHEMBL27748277 | 0.69 | DGAT1 (0.39) | DGAT1ALDH1A1KCNN4 | |
| SCHEMBL28232208 | 0.68 | DGAT1 (0.40) | DGAT1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL23033819 | 0.67 | DGAT1 (0.43) | DGAT1KCNN4TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2357248-A1 | Method for producing optically active 2-(N-substituted aminomethyl)-3-hydroxybutyric acid ester | KANEKA CORPORATION (JP) | 2011-08-17 | — | — | EP | disclosed |