Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184251 | 1.00 | DGAT1 (0.41) | DGAT1KCNN4SMN1; SMN2ALDH1A1MMP8 | |
| SCHEMBL2185566 | 1.00 | DGAT1 (0.41) | DGAT1KCNN4SMN1; SMN2ALDH1A1MMP8 | |
| Ammonia Solution, Strong SCHEMBL27748277 | 0.97 | DGAT1 (0.39) | DGAT1KCNN4SMN1; SMN2ALDH1A1 | |
| SCHEMBL12700691 | 0.81 | DGAT1 (0.42) | DGAT1KCNN4SMN1; SMN2ALDH1A1 | |
| SCHEMBL1629800 | 0.81 | DGAT1 (0.48) | DGAT1KCNN4SMN1; SMN2ALDH1A1MMP8 | |
| SCHEMBL11076263 | 0.80 | DGAT1 (0.38) | DGAT1KCNN4SMN1; SMN2CA14 | |
| Ammonia Solution, Strong SCHEMBL28085860 | 0.79 | DGAT1 (0.46) | DGAT1KCNN4SMN1; SMN2ALDH1A1MMP8 | |
| SCHEMBL12494033 | 0.77 | DGAT1 (0.39) | DGAT1KCNN4SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL20959675 | 0.77 | DGAT1 (0.39) | DGAT1KCNN4SMN1; SMN2ALDH1A1 | |
| SCHEMBL14513533 | 0.77 | DGAT1 (0.39) | DGAT1KCNN4SMN1; SMN2ALDH1A1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282909-A1 | CHEMICALLY CIRCULAR POLYHYDROXYALKANOATES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2025-09-11 | — | — | US | disclosed |
| US-20250163063-A1 | INHIBITORS OF CDK4/6 KINASE | KHORA SPV 1, LLC | 2025-05-22 | — | — | US | disclosed |
| WO-2025024707-A1 | INHIBITORS OF CDK2/4/6 KINASE | KINNATE BIOPHARMA INC. (US) | 2025-01-30 | — | — | WO | disclosed |
| EP-4469062-A1 | INHIBITORS OF CDK4/6 KINASE | Kinnate Biopharma Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-119013030-A | Inhibitors of CDK4/6 kinase | 金耐特生物制药公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023147372-A1 | INHIBITORS OF CDK4/6 KINASE | KINNATE BIOPHARMA INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-104703991-A | Macrocyclic inhibitors of flaviviridae viruses | GILEAD SCIENCES INC | 2015-06-10 | — | — | CN | disclosed |
| CN-101633655-B | Dehydrophenylahistine and analogs thereof and synthesis of dehydrophenylahistine and analogs thereof | DALIAN WANCHUN PHARMACEUTICAL CO LTD | 2014-04-30 | — | — | CN | disclosed |
| EP-2342199-B1 | Sulfonyl compounds which selectively modulate the CB2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2014-02-26 | — | — | EP | disclosed |
| US-8618292-B2 | Analogs of dehydrophenylahistins and their therapeutic use | BEYONDSPRING PHARMACEUTICALS, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-7064201-B2 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof | NEREUS PHARMACEUTICALS, INC. (US) | 2006-06-20 | — | — | US | disclosed |
| CN-1684955-A | Dehydrophenylahistine and analogs thereof and synthesis of dehydrophenylahistine and analogs thereof | NEREUS PHARMACEUTICALS INC (US) | 2005-10-19 | — | — | CN | disclosed |
| US-20050197344-A1 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof | BEYONDSPRING PHARMACEUTICALS, INC. | 2005-09-08 | — | — | US | disclosed |
| WO-2005077940-A1 | DEHYDROPHENYLAHISTINS AND ANALOGS THEREOF AND THE SYNTHESIS OF DEHYDROPHENYLAHISTINS AND ANALOGS THEREOF | NEREUS PHARMACEUTICALS, INC. (US) | 2005-08-25 | — | — | WO | disclosed |
| EP-1529044-A2 | DEHYDROPHENYLAHISTINS AND ANALOGS THEREOF AND THE SYNTHESIS OF DEHYDROPHENYLAHISTINS AND ANALOGS THEREOF | Nereus Pharmaceuticals, Inc. (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20050090667-A1 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof | BEYONDSPRING PHARMACEUTICALS, INC. | 2005-04-28 | — | — | US | disclosed |
| US-6878838-B2 | Chiral porous metal phosphonates for heterogeneous asymmetric catalysis | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-04-12 | — | — | US | disclosed |
| WO-2004084834-A2 | CHIRAL POROUS METAL PHOSPHONATES FOR HETEROGENEOUS ASYMMETRIC CATALYSIS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040192543-A1 | Chiral porous metal phosphonates for heterogeneous asymmetric catalysis | NORTH CAROLINA AT CHAPEL HILL, UNIVERSITY OF, THE | 2004-09-30 | — | — | US | disclosed |
| WO-2004054498-A2 | DEHYDROPHENYLAHISTINS AND ANALOGS THEREOF AND THE SYNTHESIS OF DEHYDROPHENYLAHISTINS AND ANALOGS THEREOF | NEREUS PHARMACEUTICALS, INC. (US) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090667-A1 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof | TPD52L2, DHPS, DCXR | DGAT1 1823/4885KCNN4 3679/4885SMN1; SMN2 4771/4885 |
| US-20250163063-A1 | INHIBITORS OF CDK4/6 KINASE | CDK4, CDK6, CDK2 | DGAT1 2885/4885KCNN4 4822/4885SMN1; SMN2 2089/4885 |
| US-20050197344-A1 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof | DHFR, DHPS, QDPR | DGAT1 1674/4885KCNN4 2870/4885SMN1; SMN2 4699/4885 |
| US-20040192543-A1 | Chiral porous metal phosphonates for heterogeneous asymmetric catalysis | ZKSCAN2, TPRKB, KHK | DGAT1 1677/4885KCNN4 167/4885SMN1; SMN2 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.