Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | IL2 | P60568 | 2/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23266386 | 0.87 | ALDH1A1 (0.35) | ABCB1ABCG2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL23266056 | 0.85 | ABCB1 (0.36) | ABCB1ABCG2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4512861 | 0.84 | HPGDS (0.40) | SMN1; SMN2KDM4ELMNATP53HPGD | |
| SCHEMBL23265365 | 0.84 | ABCB1 (0.35) | ABCB1ABCG2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL29433011 | 0.83 | ABCB1 (0.37) | ABCB1ABCG2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL21295278 | 0.83 | ABCB1 (0.37) | ABCB1ABCG2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL23265366 | 0.83 | ABCB1 (0.36) | ABCB1ABCG2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL23266054 | 0.81 | ABCB1 (0.37) | ABCB1ABCG2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL23265459 | 0.81 | ALDH1A1 (0.46) | ABCB1ABCG2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL23265498 | 0.80 | ABCB1 (0.34) | ABCB1ABCG2SMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021074309-A1 | 1-(3-QUINOLYL)-3,4-DIHYDROISOQUINOLINE DERIVATIVES AS FUNGICIDES FOR COMBATING SPECIFIC PHYTOPATHOGENS | SYNGENTA CROP PROTECTION AG (CH) | 2021-04-22 | — | — | WO | disclosed |