Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | PARG | Q86W56 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325049 | 0.87 | F10 (0.51) | F10 | |
| Hydrochloric Acid SCHEMBL2329804 | 0.84 | F10 (0.52) | F10 | |
| SCHEMBL2326821 | 0.83 | F10 (0.51) | F10 | |
| SCHEMBL8425668 | 0.81 | FNTA (0.41) | PNMTF10KCNH2DRD2DRD3 | |
| SCHEMBL8425665 | 0.80 | F10 (0.46) | HTR2CHTR2BPNMTF10DRD2 | |
| SCHEMBL8423957 | 0.80 | DRD4 (0.42) | F10PARGKCNH2DRD2DRD3 | |
| SCHEMBL2330488 | 0.79 | F10 (0.54) | F10 | |
| SCHEMBL8424198 | 0.79 | F10 (0.46) | F10 | |
| SCHEMBL2329650 | 0.78 | F10 (0.55) | F10 | |
| SCHEMBL8622746 | 0.77 | KCNH2 (0.40) | PARGKCNH2DRD2ROCK2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | disclosed |