Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | PARG | Q86W56 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CCR9 | P51686 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331634 | 0.87 | F10 (0.56) | F10PLGPROC | |
| SCHEMBL2326821 | 0.86 | F10 (0.51) | F10PLGPROCALDH1A1 | |
| SCHEMBL8425655 | 0.82 | F10 (0.46) | DRD4DRD3F10DRD2KCNH2 | |
| SCHEMBL2330488 | 0.81 | F10 (0.54) | F10PLGPROC | |
| SCHEMBL2328117 | 0.81 | F10 (0.46) | DRD4DRD3F10DRD2ROCK2 | |
| SCHEMBL2326558 | 0.80 | HTR2C (0.45) | DRD3F10DRD2PARGROCK2 | |
| SCHEMBL2329650 | 0.79 | F10 (0.55) | F10PLGPROC | |
| SCHEMBL8622746 | 0.78 | KCNH2 (0.40) | DRD2PARGROCK2ROCK1KCNH2 | |
| SCHEMBL8423964 | 0.77 | DRD4 (0.41) | DRD4DRD3F10DRD2ROCK2 | |
| SCHEMBL2325190 | 0.76 | F10 (0.68) | F10THRBPLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |