Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.46 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | PROC | P04070 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425358 | 0.83 | F10 (0.59) | F10F2PLGPLATPROC | |
| SCHEMBL2325049 | 0.82 | F10 (0.51) | F10F2PLGPROC | |
| SCHEMBL8425668 | 0.81 | FNTA (0.41) | F10F2PLGPROCPNMT | |
| SCHEMBL2326558 | 0.80 | HTR2C (0.45) | F10HTR2CHTR2BPNMTDRD2 | |
| SCHEMBL2325707 | 0.80 | F10 (0.69) | F10F2PLGPLATPROC | |
| SCHEMBL2328117 | 0.79 | F10 (0.46) | F10F2MCOLN3L3MBTL1PSEN1 | |
| SCHEMBL8423783 | 0.79 | F10 (0.72) | F10F2PLGPLATPROC | |
| SCHEMBL2334963 | 0.77 | F10 (0.54) | F10F2PLGPLATPROC | |
| SCHEMBL8622748 | 0.77 | F10 (0.43) | F10F2MCOLN3PSEN1PSEN2 | |
| SCHEMBL2325764 | 0.75 | F10 (0.41) | F10F2MCOLN3PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |