Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.90 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.90 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.90 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.90 |
| ▸ | PDE1A | P54750 | 9/20 | 0.89 |
| ▸ | PDE1B | Q01064 | 9/20 | 0.89 |
| ▸ | PDE1C | Q14123 | 9/20 | 0.89 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30902018 | 0.95 | PSMB1 (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL7650156 | 0.95 | PSMB1 (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL7650153 | 0.95 | PSMB1 (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL15648408 | 0.95 | PSMB1 (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL29822053 | 0.95 | PSMB1 (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL8767419 | 0.94 | PDE1A (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL8767418 | 0.94 | PDE1A (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL8767423 | 0.94 | PDE1A (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL8766916 | 0.92 | PDE1A (1.00) | ESR1PSMB1PSMB5PSMB2PDE1A | |
| SCHEMBL24505428 | 0.90 | ESR1 (0.91) | ESR1PSMB1PSMB5PSMB2PDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021075147-A1 | BRAP2 ACTION ENHANCER | 学校法人東京理科大学 | 2021-04-22 | — | — | WO | disclosed |