Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 14/20 | 0.76 |
| ▸ | BECN1 | Q14457 | 14/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | YAP1 | P46937 | 1/20 | 0.62 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.62 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTR1E | P28566 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23268991 | 0.87 | BCL2 (1.00) | BCL2BECN1PKMPOLB | |
| SCHEMBL23268892 | 0.86 | BCL2 (0.74) | BCL2BECN1LMNAPKMRAB9A | |
| SCHEMBL23269260 | 0.86 | BCL2 (0.75) | BCL2BECN1LMNAPKMRAB9A | |
| SCHEMBL23269377 | 0.84 | BCL2 (1.00) | BCL2BECN1 | |
| SCHEMBL23269266 | 0.84 | BCL2 (0.76) | BCL2BECN1LMNAPKMRAB9A | |
| SCHEMBL23268900 | 0.83 | BCL2 (0.83) | BCL2BECN1LMNAPKMRAB9A | |
| SCHEMBL23268993 | 0.82 | BCL2 (0.85) | BCL2BECN1LMNAPKMRAB9A | |
| SCHEMBL14541079 | 0.82 | CA1 (0.71) | BCL2BECN1LMNAKMT2AMEN1 | |
| SCHEMBL23268896 | 0.82 | BCL2 (1.00) | BCL2BECN1LMNAPKMRAB9A | |
| SCHEMBL23269264 | 0.81 | BCL2 (0.80) | BCL2BECN1LMNAPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203020-A1 | Small molecule inducers of autophagy | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-06-29 | — | — | US | disclosed |
| US-11325898-B2 | Small molecule inducers of autophagy | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-05-10 | — | — | US | disclosed |
| US-20210115024-A1 | Small molecule inducers of autophagy | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11325898-B2 | Small molecule inducers of autophagy | BECN1, SQSTM1, MAP1LC3A | BCL2 11/4885BECN1 1/4885LMNA 3830/4885 |
| US-20210115024-A1 | Small molecule inducers of autophagy | BECN1, SQSTM1, MAP1LC3A | BCL2 11/4885BECN1 1/4885LMNA 3830/4885 |
| US-20230203020-A1 | Small molecule inducers of autophagy | BECN1, SQSTM1, MAP1LC3A | BCL2 11/4885BECN1 1/4885LMNA 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.