Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23275767 | 0.86 | CA1 (0.49) | ALDH1A1CYP2C9NAMPTSMN1; SMN2LMNA | |
| SCHEMBL19303863 | 0.76 | KCNH2 (0.44) | NAMPTACLYLMNA | |
| SCHEMBL30431527 | 0.75 | ACLY (0.40) | ALDH1A1NAMPTSMN1; SMN2ACLYLMNA | |
| SCHEMBL23139776 | 0.75 | ACLY (0.40) | NAMPTACLYLMNA | |
| SCHEMBL19104168 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CYP2C9SMN1; SMN2ACLYLMNA | |
| SCHEMBL23118491 | 0.74 | MEN1 (0.62) | ALDH1A1NAMPTLMNAKDM4EMAPK1 | |
| SCHEMBL13585276 | 0.73 | ACLY (0.41) | NAMPTACLY | |
| SCHEMBL16179008 | 0.71 | — | — | |
| SCHEMBL11511836 | 0.71 | ALDH1A1 (0.83) | ALDH1A1CYP2C9SMN1; SMN2LMNAVCAM1 | |
| SCHEMBL23139930 | 0.71 | HTT (0.59) | ALDH1A1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078020-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| WO-2021078020-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| CN-110734428-A | small molecule compounds | 嘉兴特科罗生物科技有限公司 | 2020-01-31 | — | — | CN | disclosed |