Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 8/20 | 0.56 |
| ▸ | JAK3 | P52333 | 7/20 | 0.56 |
| ▸ | JAK1 | P23458 | 4/20 | 0.56 |
| ▸ | TYK2 | P29597 | 3/20 | 0.56 |
| ▸ | BTK | Q06187 | 10/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.49 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | CIT | O14578 | 1/20 | 0.49 |
| ▸ | GAK | O14976 | 1/20 | 0.49 |
| ▸ | OPA1 | O60313 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | STK16 | O75716 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27228673 | 0.90 | JAK2 (0.55) | JAK2JAK3JAK1TYK2BTK | |
| SCHEMBL23275831 | 0.88 | BTK (0.58) | JAK2JAK3JAK1TYK2BTK | |
| SCHEMBL23275806 | 0.86 | JAK2 (0.52) | JAK2JAK3JAK1TYK2BTK | |
| SCHEMBL23275663 | 0.85 | JAK2 (0.68) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL22097961 | 0.84 | JAK2 (0.51) | JAK2JAK3JAK1TYK2BTK | |
| SCHEMBL23275766 | 0.84 | JAK2 (0.62) | JAK2JAK3JAK1TYK2BTK | |
| SCHEMBL23275696 | 0.82 | CAMK2D (0.66) | JAK2JAK3JAK1TYK2BTK | |
| SCHEMBL23281857 | 0.82 | JAK3 (0.56) | JAK2JAK3JAK1TYK2BTK | |
| SCHEMBL23275768 | 0.81 | CDK2 (0.57) | JAK2JAK3JAK1TYK2BTK | |
| SCHEMBL23275693 | 0.81 | MKNK1 (0.53) | JAK2JAK3JAK1TYK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174648-A1 | Small Molecule Compound | TECHNODERMA MEDICINES INC. (CN) | 2024-05-30 | — | — | US | disclosed |
| EP-4050009-A1 | SMALL MOLECULE COMPOUND | Technoderma Medicines Pte Ltd (CN) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021078023-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| WO-2021078023-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| CN-110627775-A | Small molecule compound | 嘉兴特科罗生物科技有限公司 | 2019-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174648-A1 | Small Molecule Compound | JAK1, JAK2, TYK2 | JAK2 2/4885JAK3 4/4885JAK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.