Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327636 | 1.00 | KMT2A (0.44) | KMT2AKDM4ESMN1; SMN2RAB9AMGAM | |
| SCHEMBL2333803 | 0.80 | MEN1 (0.43) | KMT2AKDM4ESMN1; SMN2MEN1ALOX5 | |
| SCHEMBL2332343 | 0.80 | MEN1 (0.43) | KMT2AKDM4ESMN1; SMN2MEN1ALOX5 | |
| SCHEMBL2332350 | 0.80 | MEN1 (0.43) | KMT2AKDM4ESMN1; SMN2MEN1ALOX5 | |
| SCHEMBL2328850 | 0.77 | KMT2A (0.44) | KMT2AKDM4ESMN1; SMN2RAB9AMGAM | |
| SCHEMBL28948579 | 0.76 | CYP2C19 (0.54) | KDM4ESMN1; SMN2ALOX5LMNAHSD17B10 | |
| SCHEMBL13134242 | 0.73 | KDM4E (0.52) | KMT2AKDM4ESMN1; SMN2RAB9AMGAM | |
| SCHEMBL2326069 | 0.71 | AOC3 (0.39) | KMT2AKDM4EMEN1POLBCYP2C19 | |
| SCHEMBL2326062 | 0.71 | AOC3 (0.39) | KMT2AKDM4EMEN1POLBCYP2C19 | |
| SCHEMBL7506444 | 0.71 | KDM4E (0.43) | KMT2AKDM4ESMN1; SMN2RAB9AMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099947-A1 | A NEW CLASS OF HIGHLY APOPTOTIC ANTI-CANCER AGENTS | CAGIR ALI (TR) | 2011-08-18 | — | — | WO | disclosed |