Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2332343 | 1.00 | MEN1 (0.43) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL2333803 | 1.00 | MEN1 (0.43) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL5270062 | 0.87 | MEN1 (0.43) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL11353033 | 0.83 | L3MBTL1 (0.43) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL8040143 | 0.82 | THRB (0.44) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL28948579 | 0.82 | CYP2C19 (0.54) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL2327636 | 0.80 | KMT2A (0.44) | MEN1KMT2AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL2327633 | 0.80 | KMT2A (0.44) | MEN1KMT2AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL5267799 | 0.79 | UGT2B7 (0.49) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL20211629 | 0.79 | CYP3A4 (0.45) | MEN1KMT2AKDM4EALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099947-A1 | A NEW CLASS OF HIGHLY APOPTOTIC ANTI-CANCER AGENTS | CAGIR ALI (TR) | 2011-08-18 | — | — | WO | disclosed |