Triforine

Triforine

SCHEMBL23278

O=CNC(N1CCN(C(NC=O)C(Cl)(Cl)Cl)CC1)C(Cl)(Cl)Cl

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
HPGD P15428 3/20 0.34
CYP2C19 P33261 2/20 0.34
CYP1A2 P05177 1/20 0.34
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triforine SCHEMBL8064620 1.00 ALDH1A1 (0.34) ALDH1A1HPGDCYP2C19CYP1A2MAPT
Triforine SCHEMBL10335796 0.90 POLB (0.31) ALDH1A1HPGDCYP2C19CYP1A2POLB
Triforine SCHEMBL11829811 0.90 ALDH1A1 (0.39) ALDH1A1HPGDCYP2C19CYP1A2MAPT
SCHEMBL7180786 0.90 ALDH1A1 (0.44) ALDH1A1HPGDCYP2C19CYP1A2MAPT
SCHEMBL3363797 0.86 POLB (0.45) ALDH1A1HPGDCYP2C19CYP1A2MAPT
SCHEMBL9652015 0.86 POLB (0.31) ALDH1A1HPGDCYP2C19CYP1A2POLB
SCHEMBL13406758 0.86 ALDH1A1 (0.31) ALDH1A1MAPT
Hydrochloric Acid SCHEMBL10987504 0.85 POLB (0.30) POLB
Cadaverine Tartrate SCHEMBL11856072 0.75 POLB (0.33) ALDH1A1HPGDCYP2C19CYP1A2POLB
SCHEMBL9274708 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23169 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105160-A1 NOVEL AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2026-05-21 WO claimed
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
US-20260101893-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-04-16 US claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20260068884-A1 COMPOSITION USED FOR KILLING FUNGI AND METHOD FOR APPLYING COMPOSITION JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) 2026-03-12 US claimed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-4646109-A2 NATURAL LIPID PARTICLE FORMULATIONS FOR AGRICULTURAL APPLICATIONS Invaio Sciences, Inc. (US) 2025-11-12 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-0230844-A1 Fungicides comprising triazole and oligo ether groups, and mixtures thereof RHONE-POULENC AGROCHIMIE (FR) 1987-08-05 EP claimed
EP-0180263-A3 METHOD FOR CONTROLLING VASCULAR WITHERING DISEASES IN PLANTS, ESPECIALLY DUTCH ELM DISEASE Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO (NL) 1986-07-30 EP claimed
EP-0180263-A2 Method for controlling vascular withering diseases in plants, especially dutch elm disease Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO (NL) 1986-05-07 EP claimed
EP-0068442-B1 AGENT, ITS APPLICATION AND PROCESS FOR COMBATING PHYTOPATHOGENIC FUNGI AND BACTERIA VEB Berlin-Chemie (DD) 1986-03-05 EP claimed
EP-0095242-A2 Fungicidal compositions and methods of treating seeds and combating fungal pest therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-30 EP claimed
US-4405605-A Fungicidal compositions CELAMERCK GMBH & CO., KG (DE) 1983-09-20 US claimed
EP-0031454-B1 FUNGICIDAL MIXTURES CONTAINING TRIFORINE AND CARBENDAZIM AND PROCESS FOR THEIR PREPARATION CELAMERCK GmbH & Co. KG (DE) 1983-04-13 EP claimed
EP-0031454-A2 Fungicidal mixtures containing triforine and carbendazim and process for their preparation CELAMERCK GmbH & Co. KG (DE) 1981-07-08 EP claimed
US-4198410-A SALT OF ALKYLBENZENESULFONIC ACID AS EMULSIFIER CELAMERCK GMBH & CO. KG (DE) 1980-04-15 US claimed
US-3975527-A Agricultural plant protection compositions containing isomers of triforine method of use CELAMERCK GMBH & CO. KG (DT) 1976-08-17 US claimed