Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 7/20 | 0.42 |
| ▸ | BTK | Q06187 | 5/20 | 0.42 |
| ▸ | ITK | Q08881 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330210 | 0.77 | TBK1 (0.51) | TBK1EGFRSRCPIK3CA | |
| SCHEMBL27843906 | 0.76 | PIK3CA (0.53) | TBK1SRCMTORPIK3CA | |
| SCHEMBL2399990 | 0.74 | TBK1 (0.47) | TBK1SRCPIK3CA | |
| SCHEMBL27841039 | 0.73 | TBK1 (0.47) | TBK1EGFRSRCPIK3CA | |
| SCHEMBL13536585 | 0.71 | JAK2 (0.60) | HPGD | |
| SCHEMBL27824876 | 0.71 | TBK1 (0.47) | TBK1SRCMTORPIK3CA | |
| SCHEMBL992163 | 0.70 | GRM5 (0.76) | HPGDGRM5MTORPIK3CA | |
| SCHEMBL990338 | 0.70 | GRM5 (0.76) | HPGDGRM5MTORPIK3CA | |
| SCHEMBL22773723 | 0.69 | GPR183 (0.62) | HPGDGRM5 | |
| SCHEMBL27112164 | 0.67 | TEK (0.51) | TBK1EGFRBLKSYKPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055077-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP1A2, PNPO | HPGD 3904/4885TBK1 4529/4885GRM5 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.