Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.51 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843906 | 0.84 | PIK3CA (0.53) | TBK1ULK1ADORA2BPIK3CAMEN1 | |
| SCHEMBL27841039 | 0.82 | TBK1 (0.47) | TBK1ULK1EGFRFGFR1ADORA2B | |
| SCHEMBL2327107 | 0.82 | FGFR2 (0.56) | TBK1EGFRPIK3CAMEN1KMT2A | |
| SCHEMBL2399990 | 0.81 | TBK1 (0.47) | TBK1ULK1ADORA2BPIK3CAMEN1 | |
| SCHEMBL2327157 | 0.81 | SMN1; SMN2 (0.50) | EGFRMEN1KMT2AUSP2CCNB2 | |
| SCHEMBL2322576 | 0.81 | EPHB4 (0.59) | TBK1EGFRFGFR1PIK3CAPIK3CB | |
| SCHEMBL27824876 | 0.80 | TBK1 (0.47) | TBK1ULK1ADORA2BPIK3CAMEN1 | |
| SCHEMBL27824872 | 0.78 | FGFR3 (0.58) | EGFRKMT2APIK3CGKDREPHB4 | |
| SCHEMBL2326760 | 0.78 | CDK1 (0.51) | TBK1EGFRFGFR1MEN1KMT2A | |
| SCHEMBL2330481 | 0.78 | KDR (0.46) | CCNB2CDK1CDK4CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239160-A | Substituted (pyridyl) -azinylamine derivatives as fungicides | BAYER CROPSCIENCE SA | 2011-11-09 | — | — | CN | claimed |
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | claimed |
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | claimed |
| WO-2010055077-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | claimed |
| CN-102239160-A | Substituted (pyridyl) -azinylamine derivatives as fungicides | BAYER CROPSCIENCE SA | 2011-11-09 | — | — | CN | disclosed |
| CN-102216287-A | Fungicide heterocyclyl-triazinyl-amino derivatives | BAYER CROPSCIENCE SA | 2011-10-12 | — | — | CN | disclosed |
| US-20110237594-A1 | FUNGICIDE HERETOCYCLYL-TRIAZINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| EP-2356104-A1 | FUNGICIDE HETEROCYCLYL-TRIAZINYL-AMINO DERIVATIVES | Bayer CropScience AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055077-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010055078-A1 | FUNGICIDE HETEROCYCLYL-TRIAZINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237594-A1 | FUNGICIDE HERETOCYCLYL-TRIAZINYL-AMINO DERIVATIVES | CYP4X1, RDX, PRXL2A | TBK1 3526/4885ULK1 2372/4885EGFR 3350/4885 |
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP1A2, PNPO | TBK1 4529/4885ULK1 2684/4885EGFR 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.