Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | RBP4 | P02753 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | LCAT | P04180 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15662916 | 0.95 | PKM (0.54) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| SCHEMBL19658658 | 0.89 | ACACB (0.54) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| SCHEMBL19652155 | 0.87 | ADRB1 (0.51) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| SCHEMBL3719957 | 0.85 | ADRB1 (0.49) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| SCHEMBL895533 | 0.83 | KDM4E (0.60) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| SCHEMBL1728756 | 0.82 | CHRM4 (0.59) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| SCHEMBL15655254 | 0.81 | ADRB1 (0.50) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| SCHEMBL2324834 | 0.81 | CHRM4 (0.68) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| SCHEMBL17753021 | 0.81 | ADRB1 (0.56) | ADRB1RBP4PKMSLC6A7CHRM4 | |
| Hydrochloric Acid SCHEMBL17748980 | 0.81 | ADRB1 (0.58) | ADRB1RBP4PKMSLC6A7CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356108-B1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-10-15 | — | — | EP | disclosed |
| EP-2356108-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055267-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-05-20 | — | — | WO | disclosed |