SCHEMBL23280862

SCHEMBL23280862

Nc1cc2sc3c4sc(N)cc4sc3c2s1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.32
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12681760 0.91 GPR35 (0.39) GPR35BACE1
SCHEMBL18909170 0.82 GPR35 (0.34) GPR35
SCHEMBL18909198 0.81 GPR35 (0.33) GPR35
SCHEMBL18909187 0.74 GPR35 (0.35) GPR35
SCHEMBL5039885 0.74 BACE1 (0.39) BACE1
SCHEMBL5039766 0.72 PKM (0.33)
SCHEMBL5044368 0.68 BACE1 (0.38) BACE1
SCHEMBL5035883 0.65
SCHEMBL4420026 0.65 BACE1 (0.39) BACE1
SCHEMBL20173340 0.63 PKM (0.47) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551635-B1 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2021-04-28 EP disclosed